https://mobirise.com/

Full list of Publications

Publications (from 2010)
  • Eyre, N. S., Aloia, A. L., Joyce, M. A., Chulanetra, M., Tyrrell, D. L., & Beard, M. R. (2017). Sensitive luminescent reporter viruses reveal appreciable release of hepatitis C virus NS5A protein into the extracellular environment. Virology, 507, 20-31. doi:10.1016/j.virol.2017.04.003
  • Eyre, N., Hampton-Smith, R., Aloia, A., Eddes, J., Simpson, K., Hoffmann, P., & Beard, M. (2016). Phosphorylation of NS5A Serine-235 is essential to hepatitis C virus RNA replication and normal replication compartment formation. Virology, 491, 27-44. doi:10.1016/j.virol.2016.01.018
  • Fiches, G., Eyre, N., Aloia, A., Van Der Hoek, K., Betz-Stablein, B., Luciani, F., . . . Beard, M. (2016). HCV RNA traffic and association with NS5A in living cells. Virology, 493, 60-74. doi:10.1016/j.virol.2016.02.016
  • Awan, Z., Tay, E., Eyre, N., Wu, L., Beard, M., Boo, I., . . . Douglas, M. (2016). Calsyntenin-1 mediates hepatitis C virus replication. Journal of General Virology, 97(8), 1877-1887. doi:10.1099/jgv.0.000511
  • Clarke, J., Davies, L., Calvert, J., Gliddon, B., Al Shujari, W., Aloia, A., . . . Carr, J. (2016). Reduction in sphingosine kinase 1 influences the susceptibility to dengue virus infection by altering antiviral responses. Journal of General Virology, 97(1), 95-109. doi:10.1099/jgv.0.000334
  • Milic, N., Davis, S., Carr, J., Isberg, S., Beard, M., & Helbig, K. (2015). Sequence analysis and characterisation of virally induced viperin in the saltwater crocodile (Crocodylus porosus). Developmental and Comparative Immunology, 51(1), 108-115. doi:10.1016/j.dci.2015.03.001
  • Calvert, J., Helbig, K., Dimasi, D., Cockshell, M., Beard, M., Pitson, S., . . . Carr, J. (2015). Dengue virus infection of primary endothelial cells induces innate immune responses, changes in endothelial cells function and is restricted by interferon-stimulated responses. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 35(8), 654-665. doi:10.1089/jir.2014.0195
  • Narayana, S., Helbig, K., McCartney, E., Eyre, N., Bull, R., Eltahla, A., . . . Beard, M. (2015). The interferon-induced transmembrane proteins, IFITM1, IFITM2 and IFITM3 inhibit hepatitis C virus entry. Journal of Biological Chemistry, 290(43), 25946-25959. doi:10.1074/jbc.M115.657346
  • Green, T., Speck, P., Geng, L., Raftos, D., Beard, M., & Helbig, K. (2015). Oyster viperin retains direct antiviral activity and its transcription occurs via a signalling pathway involving a heat-stable haemolymph protein. Journal of General Virology, 96(12), 3587-3597. doi:10.1099/jgv.0.000300
  • Aloia, A., Eyre, N., Black, S., Bent, S., Gaeguta, A., Guo, Z., . . . Beard, M. (2015). Generation of a chimeric hepatitis C replicon encoding a genotype-6a NS3 protease and assessment of boceprevir (SCH503034) sensitivity and drug-associated mutations.. Antiviral therapy, 20(3), 271-280. doi:10.3851/IMP2850
  • Tse, E., Helbig, K., Van der Hoek, K., McCartney, E., Van der Hoek, M., George, J., & Beard, M. (2015). Fatty acids induce a pro-inflammatory gene expression profile in Huh-7 cells that attenuates the anti-HCV action of interferon. Journal of Interferon and Cytokine Research, 35(5), 392-400. doi:10.1089/jir.2014.0165
  • Mina, M., Luciani, F., Cameron, B., Bull, R., Beard, M., Booth, D., & Lloyd, A. (2015). Resistance to hepatitis C virus: potential genetic and immunological determinants. The Lancet Infectious Diseases, 15(4), 451-460. doi:10.1016/S1473-3099(14)70965-X
  • Tse, E. Y., Helbig, K. J., Van der Hoek, K., McCartney, E. M., George, J., & Beard, M. R. (2014). FATTY ACIDS INDUCE A PRO-INFLAMMATORY GENE EXPRESSION PROFILE IN HUH-7 CELLS AND ATTENUATE THE ANTI-HCV ACTION OF INTERFERON. Poster session presented at the meeting of JOURNAL OF HEPATOLOGY. London, ENGLAND: ELSEVIER SCIENCE BV. Retrieved from http://gateway.webofknowledge.com/
  • Beard, M., Ffrench, R., Gowans, E., Helbig, K., Eyre, N., Douglas, M., . . . Drummer, H. (2014). A summary of the 20th International Symposium on Hepatitis C Virus and Related Viruses. Gastroenterology, 147(1), e1-e4. doi:10.1053/j.gastro.2014.05.022
  • Eyre, N., Fiches, G., Aloia, A., Helbig, K., McCartney, E., McErlean, C., . . . Beard, M. (2014). Dynamic imaging of the hepatitis C virus NS5A protein during a productive infection. Journal of Virology, 88(7), 3636-3652. doi:10.1128/JVI.02490-13
  • Helbig, K., & Beard, M. (2014). The role of viperin in the innate antiviral response. Journal of Molecular Biology, 426(6), 1210-1219. doi:10.1016/j.jmb.2013.10.019
  • Eyre, N., & Beard, M. (2014). HCV NS5A inhibitors disrupt replication factory formation: a novel mechanism of antiviral action. Gastroenterology, 147(5), 959-962. doi:10.1053/j.gastro.2014.09.024
  • Eyre, N. S., & Beard, M. R. (2014). A mechanism for HCV NS5A-directed antiviral therapy. Gastroenterology, 147(5), 946-947. doi:10.1053/j.gastro.2014.09.021 Eyre, N. S., Helbig, K. J., & Beard, M. R. (2014). Current and future targets of antiviral therapy in the hepatitis C virus life cycle. Future Virology, 9(11), 947-965. doi:10.2217/FVL.14.83
  • Muller, K. R., Eyre, N. S., Van der Hoek, K. H., Li, K., & Beard, M. R. (2013). The effect of hepatitis C virus-infected Huh-7 cells on 'bystander' cells. Poster session presented at the meeting of Journal of Gastroenterology and Hepatology. Melbourne, Vic.: Wiley. doi:10.1111/jgh.12365
  • McCartney, E., Helbig, K., Narayana, S., Eyre, N., Aloia, A., & Beard, M. (2013). Signal transducer and activator of transcription 3 is a proviral host factor for hepatitis C virus. Hepatology, 58(5), 1558-1568. doi:10.1002/hep.26496
  • Carr, J., Kua, T., Clarke, J., Calvert, J., Zebol, J., Beard, M., & Pitson, S. (2013). Reduced sphingosine kinase 1 activity in dengue virus type-2 infected cells can be mediated by the 3' untranslated region of dengue virus type-2 RNA. Journal of General Virology, 94(PART 11), 2437-2448. doi:10.1099/vir.0.055616-0
  • Moriconi, F., Beard, M., & Yuen, L. (2013). Bioinformatics methods for the analysis of hepatitis viruses. Antiviral Therapy, 18(3 PARTB), 531-539. doi:10.3851/IMP2613
  • Helbig, K., Carr, J., Calvert, J., Wati, S., Clarke, J., Eyre, N., . . . Beard, M. (2013). Viperin is induced following dengue virus type-2 (DENV-2) infection and has anti-viral actions requiring the C-terminal end of viperin. PLoS Neglected Tropical Diseases, 7(4), 1-14. doi:10.1371/journal.pntd.0002178
  • Aloia, A. L., Carr, J., Eyre, N. S., Locarnini, S., Lemon, S., & Beard, M. R. (2012). Development of a genotype 6a/1b chimeric replicon for testing of direct acting antivirals against the HCV protease. Poster session presented at the meeting of HEPATOLOGY. Boston, MA: WILEY-BLACKWELL. Retrieved from http://gateway.webofknowledge.com/
  • Tse, E., & Beard, M. (2012). Mechanisms of action of antiviral drugs: the interferons. In G. McCaughan, J. McHutchison, & J. -M. Pawlotsky (Eds.), Advanced therapy for hepatitis C (pp. 25-35). United Kingdom: Wiley-Blackwell. doi:10.1002/9781444346343.ch4
  • Beard, M. (2012). HCV replication. In G. McCaughan, J. McHutchison, & J. -M. Pawlotsky (Eds.), Advanced therapy for hepatitis C (pp. 1-11). United Kingdom: Wiley-Blackwell. doi:10.1002/9781444346343.ch1
  • Aloia, A., Locarnini, S., & Beard, M. (2012). Antiviral resistance and direct-acting antiviral agents for HCV. Antiviral Therapy, 17(6 PART B), 1147-1162. doi:10.3851/IMP2426
  • Nasr, N., Maddocks, S., Turville, S., Harman, A., Woolger, N., Helbig, K., . . . Cunningham, A. (2012). HIV-1 infection of human macrophages directly induces viperin which inhibits viral production. Blood, 120(4), 778-788. doi:10.1182/blood-2012-01-407395
  • Phillips, R., Helbig, K., Van Der Hoek, K., Seth, D., & Beard, M. (2012). Osteopontin increases hepatocellular carcinoma cell growth in a CD44 dependant manner. World Journal of Gastroenterology, 18(26), 3389-3399. doi:10.3748/wjg.v18.i26.3389
  • Helbig, K., & Beard, M. (2012). The interferon signaling pathway genes as biomarkers of hepatitis C virus disease progression and response to treatment. Biomarkers in Medicine, 6(2), 141-150. doi:10.2217/bmm.12.9
  • Keoshkerian, E., Helbig, K., Beard, M., Zaunders, J., Seddiki, N., Kelleher, A., . . . Lloyd, A. (2012). A novel assay for detection of hepatitis C virus-specific effector CD4⁺ T cells via co-expression of CD25 and CD134. Journal of Immunological Methods, 375(1-2), 148-158. doi:10.1016/j.jim.2011.10.004
  • McCartney, E. M., Helbig, K. J., & Beard, M. R. (2011). THE ROLE OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3 (STAT3) IN THE HCV LIFE CYCLE. In JOURNAL OF HEPATOLOGY Vol. 54 (pp. S307). Berlin, GERMANY: ELSEVIER SCIENCE BV. Retrieved from http://gateway.webofknowledge.com/
  • Thompson, A., Locarnini, S., & Beard, M. (2011). Resistance to anti-HCV protease inhibitors. Current Opinion in Virology, 1(6), 599-606. doi:10.1016/j.coviro.2011.10.001
  • Suzuki, T., Ishida, T., Yamagishi, M., Ahlenstiel, C., Swaminathan, S., Marks, K., . . . Kelleher, A. (2011). Transcriptional gene silencing of HIV-1 through promoter targeted RNA is highly specific. RNA Biology, 8(6), 1035-1046. doi:10.4161/rna.8.6.16264
  • Helbig, K., Eyre, N., Yip, L., Narayana, S., Li, K., Fiches, G., . . . Beard, M. (2011). The antiviral protein viperin inhibits hepatitis C virus replication via interaction with nonstructural protein 5A. Hepatology, 54(5), 1506-1517. doi:10.1002/hep.24542
  • Fernandez, S., Tanaskovic, S., Helbig, K., Rajasuriar, R., Kramski, M., Murray, J., . . . French, M. (2011). CD4⁺ T-cell deficiency in HIV patients responding to antiretroviral therapy is associated with increased expression of interferon-stimulated genes in CD4⁺ T cells. Journal of Infectious Diseases, 204(12), 1927-1935. doi:10.1093/infdis/jir659
  • Berzsenyi, M., Woollard, D., McLean, C., Preiss, S., Perreau, V., Beard, M., . . . Roberts, S. (2011). Down-regulation of intra-hepatic T-cell signaling associated with GB virus C in a HCV/HIV co-infected group with reduced liver disease. Journal of Hepatology, 55(3), 536-544. doi:10.1016/j.jhep.2010.12.021
  • McCartney, E., Eyre, N., & Beard, M. (2011). Border patrol intensifies for hepatitis C virus entry. Hepatology, 54(4), 1472-1475. doi:10.1002/hep.24586
  • Wati, S., Rawlinson, S., Ivanov, R., Dorstyn, L., Beard, M., Jans, D., . . . Carr, J. (2011). Tumour necrosis factor alpha (TNF-α) stimulation of cells with established dengue virus type 2 infection induces cell death that is accompanied by a reduced ability of TNF-α to activate nuclear factor κB and reduced sphingosine kinase-1 activity. Journal of General Virology, 92(4), 807-818. doi:10.1099/vir.0.028159-0
  • Berzsenyi, M., Roberts, S., Preiss, S., Woollard, D., Beard, M., Skinner, N., . . . Visvanathan, K. (2011). Hepatic TLR2 & TLR4 expression correlates with hepatic inflammation and TNF-α in HCV & HCV/HIV infection. Journal of Viral Hepatitis, 18(12), 852-860. doi:10.1111/j.1365-2893.2010.01390.x
  • Eyre, N., Drummer, H., & Beard, M. (2010). The SR-BI partner PDZK1 facilitates Hepatitis C virus entry. PLoS Pathogens, 6(10), 1-14. doi:10.1371/journal.ppat.1001130
  • Osna, N., White, R., Donohue, T., Beard, M., Tuma, D., & Kharbanda, K. (2010). Impaired methylation as a novel mechanism for proteasome suppression in liver cells. Biochemical and Biophysical Research Communications, 391(2), 1291-1296. doi:10.1016/j.bbrc.2009.12.074
  • Eyre, N., & Beard, M. (2010). Hepatitis C virus infection in living color. Hepatology, 51(5), 1852-1855. doi:10.1002/hep.23695
  • McCartney, E., & Beard, M. (2010). Impact of alcohol on hepatitis C virus replication and interferon signaling. World Journal of Gastroenterology, 16(11), 1337-1343. doi:10.3748/wjg.v16.i11.1337